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After ZnCl2 administration, we could observe a improving of the two investigated biomarkers. MDA level becomes compared with that from cyclophosphamide group. A reduced level of MDA usually suggests that the amplitude of the oxidative stress considerably diminished [48, 49]. Our experimental study sustains the efficiency of antioxidants in chemotherapy, when oxidative stress is triggered as an important contributor mechanism for tissular alterations, pinpointing a relevant activity of two distinct seric biomarkers, MDA and GPx.

We consider zinc as may contribute to reduce the effects of cyclophosphamide-induced oxidative stress on female rats genital system, protection sustained by the evidence of MDA activity medicamente antiparazitare populare and GPx level increase; based on our observation, it turns out that zinc can be used as supplemental antioxidant in chemotherapy targeting female genital system.

A Voice for Epithelioid Sarcoma – Nick Saleum’s Cancer Journey

Zinc improves the local response to oxidative stress and reduces cyclophosphamide limitations in therapy. References 1. Food Sci.

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LUPU, V. Allergy, 88,p. INCE, S.

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WEI, X. Update, 13, no.

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YIN, H. Redox Signal, 15, no. CHEN, J.

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